The director of the nation’s top public health agency, Susan Monarez, was fired by President Donald Trump himself late Wednesday because she wasn’t “aligned with the president’s mission†and refused to resign, according to the White House press secretary. Monarez’s lawyers said she was targeted for standing up for science.

Four other agency leaders resigned on Wednesday. “We knew ... if she leaves, we don’t have scientific leadership anymore, †one of the officials, . “We were going to see if she was able to weather the storm. And when she was not, we were done.â€

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