PORTLAND, Ore. (AP) — Nike co-founder Phil Knight and his wife Penny Knight have pledged to donate $2 billion to Oregon Health & Science University’s Knight Cancer Institute, the school announced Thursday, describing it as the largest single gift to a U.S. university.

“This gift is an unprecedented investment in the millions of lives burdened with cancer, especially patients and families here in Oregon,†OHSU President Shereef Elnahal said in a statement.

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